The oncomir face of microRNA-206: A permanent miR-206 transfection study
نویسندگان
چکیده
منابع مشابه
Muscle-specific microRNA miR-206 promotes muscle differentiation
Three muscle-specific microRNAs, miR-206, -1, and -133, are induced during differentiation of C2C12 myoblasts in vitro. Transfection of miR-206 promotes differentiation despite the presence of serum, whereas inhibition of the microRNA by antisense oligonucleotide inhibits cell cycle withdrawal and differentiation, which are normally induced by serum deprivation. Among the many mRNAs that are do...
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MicroRNAs (miRs) are small non-coding RNAs that negatively regulate gene expression by binding to the 3` untranslated regions (3`UTR) of their target mRNAs. MiRs were shown to play pivotal roles in tissue development and function and are also involved in the pathogenesis of various diseases including cancer. MicroRNA-206, which belongs to the group of so-called "myomiRs", is one of the most stu...
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MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene silencing. A small number of striated muscle-specific miRNAs have been identified and shown to have an important role in myogenesis, embryonic muscle growth and cardiac function and hypertrophy. One of these myomiRs (myo=muscle+miR=miRNA), miR-206, is unique in that it is only expressed in skeletal muscle. T...
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Lung cancer is a deadly disease that ends numerous lives around the world. MicroRNAs (miRNAs) are a group of non-coding RNAs involved in a variety of biological processes, such as cell growth, organ development, and tumorigenesis. The miR-206/133b cluster is located on the human chromosome 6p12.2, which is essential for growth and rebuilding of skeletal muscle. The miR-206/133b cluster has been...
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Propoxur and methyl parathion are nonsystemic insecticide used for the control of various chewing and sucking insects. Exposure to these pesticides may cause genotoxic effects in nontarget organisms including man. In the present set of investigations, mutagenicity of pesticides propoxur and methyl parathion was studied by applying dominant lethal test (DLT) on quinquefasciatus taken as an exper...
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ژورنال
عنوان ژورنال: Experimental Biology and Medicine
سال: 2018
ISSN: 1535-3702,1535-3699
DOI: 10.1177/1535370218795406